118043-69-9

Basic information

• Product Name: 4-amino-7-{[(1,3-dihydroxypropan-2-yl)oxy]methyl}-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile
• Synonyms: 7H-Pyrrolo(2,3-d)pyrimidine-5-carbonitrile, 4-amino-7-((2-hydroxy-1-(hydroxymethyl)ethoxy)methyl)-; 7H-Pyrrolo[2,3-d]pyrimidine-5-carbonitrile, 4-amino-7-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-
• CAS NO: 118043-69-9
• Molecular Formula: C₁₁H₁₃N₅O₃
• Molecular Weight: 263.2526
• Mol File: 118043-69-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 629.7°C at 760 mmHg
• Flash Point: 334.7°C
• Density: 1.57g/cm³
• Vapor Pressure: 1E-16mmHg at 25°C
• Refractive Index: 1.705
• CAS DataBase Reference: 4-amino-7-{[(1,3-dihydroxypropan-2-yl)oxy]methyl}-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-amino-7-{[(1,3-dihydroxypropan-2-yl)oxy]methyl}-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile(118043-69-9)
• EPA Substance Registry System: 4-amino-7-{[(1,3-dihydroxypropan-2-yl)oxy]methyl}-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile(118043-69-9)

Safety Data

• Hazardous Substances Data: 118043-69-9(Hazardous Substances Data)

Upstream product

• 118043-67-7 2-amino-5-cyano-7-<<1,3-bis(benzyloxy)-2-propoxy>methyl>pyrrolo<2,3-d>pyrimidine 
• 127945-43-1 <<1,3-bis(benzyloxy)-2-propoxy>methyl>-2-amino-3,4-dicyanopyrrole 
• 19393-83-0 4-amino-6-bromo-5-cyanopyrrolo[2,3-d]pyrimidine 
• 118043-66-6 4-amino-6-bromo-5-cyano-7-<<1,3-bis(benzyloxy)-2-propoxy>methyl>pyrrolo<2,3-d>pyrimidine 

Downstream Products

• 118043-70-2 4-amino-7-<(1,3-dihydroxy-2-propoxy)methyl>pyrrolo<2,3-d>pyrimidine-5-carboxamide 

Relevant articles and documents

Acyclic pyrrolo ?2,3-d!pyrimidine analogs as antiviral agents

This invention relates to the use of acyclic substituted pyrrolo?2,3-d!pyrimidine nucleoside analogs in the treatment of viral infections. Such substituted compounds retain antiviral properties present in their parent compounds, yet exhibit significantly decreased levels of cytotoxicity, thereby having therapeutic potential as antiviral agents.

Synthesis and Antivirial Activity of Some Acyclic and C-Acyclic Pyrrolopyrimidine Nucleoside Analogues

A series of acyclic and C-acyclic 7-deazapurine nucleosides have been synthesized and tested for antivirial activity.Reaction of the sodium salt of 2-amino-3,4-bis(aminocarbonyl)-5-(methylthio)pyrrole (6) with an appropriate electrophile gave pyrrole nucl