1180490-34-9Relevant academic research and scientific papers
Nickel/Lewis acid-catalyzed carbocyanation of alkynes using acetonitrile and substituted acetonitriles
Yada, Akira,Yukawa, Tomoya,Idei, Hiroaki,Nakao, Yoshiaki,Hiyama, Tamejiro
experimental part, p. 619 - 634 (2010/08/08)
Nickel/Lewis acid dual catalysis is found to effect the carbocyanation reaction of alkynes using acetonitrile and substituted acetonitriles to give a range of variously substituted acrylonitriles. The addition of propionitrile across alkynes is also demonstrated briefly to give the corresponding ethylcyanation products in good yields, whereas the reaction of butyronitrile gives significant amounts of hydrocyanation products due possibly to β hydride elimination of a propylnickel intermediate. The reaction of optically active α phenylpropionitrile suggests a reaction mechanism that involves oxidative addition of a CCN bond with retention of its absolute configuration.
Nickel/AlMe2Cl-catalysed carbocyanation of alkynes using arylacetonitriles
Yada, Akira,Yukawa, Tomoya,Nakao, Yoshiaki,Hiyama, Tamejiro
supporting information; experimental part, p. 3931 - 3933 (2010/01/06)
Nickel/Lewis acid dual catalysis was found to effect the carbocyanation reaction of alkynes using arylacetonitriles, giving a range of triply substituted acrylonitriles; the reaction of optically active α-phenylpropionitrile suggested a reaction mechanism
