1180645-87-7Relevant articles and documents
Dual functionalization of allene: facile construction of heteropolycycles mediated by Bronsted acid
Mori, Keiji,Sueoka, Shosaku,Akiyama, Takahiko
, p. 628 - 629 (2011/04/22)
A facile construction of a heteropolycyclic framework is developed by exploiting the dual functionalization of allene. On treatment of phenethyl alcohol or amine bearing a terminal allene with the Bronsted acid, two consecutive reactions to allene, nucleophilic addition of heteroatom and the Friedel-Crafts reaction, occurred to give 2-oxa-or azabicyclo[2.2.2]octane skeleton. Copyright