1180676-77-0

Basic information

• Product Name: ethyl 5-(4-ethylphenyl)-3-phenylpent-2-enoate
• Synonyms: ethyl 5-(4-ethylphenyl)-3-phenylpent-2-enoate
• CAS NO: 1180676-77-0
• Molecular Weight: 308.42
• Mol File: 1180676-77-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: ethyl 5-(4-ethylphenyl)-3-phenylpent-2-enoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 5-(4-ethylphenyl)-3-phenylpent-2-enoate(1180676-77-0)
• EPA Substance Registry System: ethyl 5-(4-ethylphenyl)-3-phenylpent-2-enoate(1180676-77-0)

Safety Data

• Hazardous Substances Data: 1180676-77-0(Hazardous Substances Data)

Upstream product

• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 156186-40-2 3-(4-ethylphenyl)-1-phenylpropan-1-one 

Downstream Products

• 1180676-49-6 (E)-5-(4-ethylphenyl)-3-phenylpent-2-enoic acid 

Relevant articles and documents

ALLOSTERIC PROTEIN KINASE MODULATORS

The invention provides specific small molecule compounds that allosterically regulate the activity or modulate protein-protein interactions of AGC protein kinases and the Aurora family of protein kinases, methods for their production, pharmaceutical compositions comprising same, and their use for preparing medicaments for the treatment and prevention of diseases related to abnormal activities of AGC protein kinases or of protein kinases of the Aurora family.

3,5-Diphenylpent-2-enoic acids as allosteric activators of the protein kinase PDK1: Structure-activity relationships and thermodynamic characterization of binding as paradigms for PIF-binding pocket-targeting compounds

The modulation of protein kinase activities by low molecular weight compounds is a major goal of current pharmaceutical developments. In this line, important efforts are directed to the development of drugs targeting the conserved ATP binding site. Howeve