118068-56-7Relevant articles and documents
CYCLIZATION OF NITRILES. XXIV. REACTIONS OF CYANAMIDE DERIVATIVES OF THIOCARBAMIC ACIDS WITH CYANOTHIOACETAMIDE. CRYSTAL STRUCTURE OF 2-ALLYLAMINO-4-AMINO-5-BENZOYL-1,3-THIAZOLE
Nesterov, V. N.,Sharanin, Yu. A.,Shestopalov, A. M.,Shklover, V. E.,Struchkov, Yu. T.
, p. 762 - 770 (2007/10/02)
2-Allylamino-4-amino-5-aroyl-1,3-thiazoles were obtained from S-alkylisoureas.An x-ray crystallographic investigation of 2-allylamino-4-amino-5-benzoyl-1,3-thiazole was undertaken.Dimethyl dithiocarbamate was used in the synthesis of 2-amino-4-methylthio-5-cyano-1H-pyrimidine-6-thione and, from the latter, 4-allylthio-2-amino-6-methylthio-5-cyanopyrimidine.The latter is easily quaternized by the action of iodine to 4-amino-3-iodomethyl-7-methylthio-8-cyano-2,3-dihydrothiazolopyrimidinium triiodide.In reaction with iodine 2-allylamino-1,3-thiazoles form N-allyl-N-iodo derivatives of 1,3-thiazole and not imidazothiazolium salts.