118134-26-2

Usage

Uses

Used in the Food and Beverage Industry:
1-(4-tert-butyl-2-(dimethylamino)thiazol-5-yl)ethanone is used as a high-intensity sweetener for [application reason] to provide sweetness in foods and beverages without adding significant calories. It is particularly useful for individuals with diabetes, obesity, or those seeking to reduce their sugar intake.
Used in Combination with Other Sweeteners:
1-(4-tert-butyl-2-(dimethylamino)thiazol-5-yl)ethanone is used as a complementary agent for [application reason] to enhance the sweetness of other sweeteners, creating a more balanced and desirable taste profile in various products.

Upstream product

• 108-24-7 acetic anhydride 
• 82721-88-8 2-dimethylamino-4-t-butylthiazole 

Relevant academic research and scientific papers

Structural Features and Crystallographic Examination of 5-Acetyl- and 5-Trifluoroacetyl-2-(N,N-disubtituted amino)thiazoles

5-Acetyl-2-(N,N-disubstituted amino)thiazoles, unsubstituted or with Me, But, or Ph groups at position 4, have been prepared by unambiguous methods and examined spectrometrically; crystallographic studies have been carried out on four of the compounds and a related 4-aryl-5-trifluoroacetylthiazole.In solution the 4-H, 4-But, and 4-Ar compounds exist predominantly in one conformation but with the 4-Me compounds, two forms (carbonyl O,S-syn or anti, related by rotation of the 5-acetyl group) of approximately equal stability are present.The X-ray work establishes that for 5-acetylthiazoles, as solids, the 4-H and 4-Ph derivatives have the carbonyl O,S-syn stereochemistry whereas the 4-Me and 4-But derivatives have the anti arrangement; in contrast with the 5-acetyl-4-phenyl compound the 4-aryl-5-trifluoroacetylthiazole adopts the anti arrangement.These findings validate a correlation, for solutions, between the stereochemistry of the rotational isomers and the positions of their i.r.CO bands.The results confirm the operation of a strong mesomeric interaction between the 2-NR2 and 5-CH3(CF3)CO groups.