118141-91-6

Upstream product

• 62484-42-8 2-Chloro-3,4-dihydro-4-oxo-6-methylquinazoline 
• 112888-80-9 Diethyl N-<4--N-prop-2-ynylamino>benzoyl>-L-glutamate 
• 118111-59-4 6-Bromomethyl-2-chloro-3H-quinazolin-4-one 
• 76858-72-5 diethyl N-(4-(prop-2-ynylamino)benzoyl)-L-glutamate 
• 118111-74-3 (S)-2-(4-{[2-(Carboxymethyl-amino)-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl]-prop-2-ynyl-amino}-benzoylamino)-pentanedioic acid diethyl ester 

Relevant academic research and scientific papers

Quinazoline antifolate thymidylate synthase inhibitors: nitrogen, oxygen, sulfur, and chlorine substituents in the C2 position

The synthesis of 16 new N10-propargylquinazoline antifolates with methylamino, ethylamino, (2-aminoethyl)amino, [2-(dimethylamino)ethyl]amino, (2-hydroxyethyl)amino, (carboxymethyl)amino, dimethylamino, imidazol-1-yl, methoxy, ethoxy, phenoxy,