1181752-75-9Relevant academic research and scientific papers
Discovery of leukotriene A4 hydrolase inhibitors using metabolomics biased fragment crystallography
Davies, Douglas R.,Mamat, Bjorn,Magnusson, Olafur T.,Christensen, Jeff,Haraldsson, Magnus H.,Mishra, Rama,Pease, Brian,Hansen, Erik,Singh, Jasbir,Zembower, David,Kim, Hidong,Kiselyov, Alex S.,Burgin, Alex B.,Gurney, Mark E.,Stewart, Lance J.
, p. 4694 - 4715 (2009)
We describe a novel fragment library termed fragments of life (FOL) for structure-based drug discovery. The FOL library includes natural small molecules of life, derivatives thereof, and biaryl protein architecture mimetics. The choice of fragments facili
