1182275-47-3

Upstream product

• 1065524-59-5 3-(2-acetamido-4,6-O-benzylidene-2-deoxy-α-D-glucopyranosyl)propene 
• 1182275-42-8 3-(2-acetamido-4,6-O-(R)-benzylidene-3-O-tert-butyldimethylsilyl-2-deoxy-α-D-glucopyranosyl)prop-1-ene 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 19236-58-9 dibenzyl methylphosphonate 
• 1182275-44-0 methyl 2-(2-acetamido-4,6-O-(R)-benzylidene-3-O-tert-butyldimethylsilyl-2-deoxy-α-D-glucopyranosyl)acetate 

Downstream Products

• 1182275-48-4 benzyl 3-(2-acetamido-4,6-O-(R)-benzylidene-3-O-tert-butyldimethylsilyl-2-deoxy-α-D-glucopyranosyl)-2-oxopropylphosphonate 
• 1352575-71-3 dibenzyl 3-(2-acetamido-2-deoxy-α-D-glucopyranosyl)-2-oxopropylphosphonate 
• 1352575-72-4 benzyl 3-(2-acetamido-2-deoxy-α-D-glucopyranosyl)-2-oxopropylphosphonate 
• 1352575-78-0 benzyl (R)-citronellyl 3-(2-acetamido-2-deoxy-α-D-glucopyranosyl)-2-oxopropylphosphonate 
• 1352575-70-2 benzyl (R)-citronellyl 3-(2-acetamido-4,6-O-(R)-benzylidene-3-O-tert-butyldimethylsilyl-2-deoxy-α-D-glucopyranosyl)-2-oxopropylphosphonate 

Relevant academic research and scientific papers

Synthesis and biological evaluation of potential new inhibitors of the bacterial transferase MraY with a β-ketophosphonate structure

Stable analogs of bacterial transferase MraY substrate or product with a pyrophosphate surrogate in their structure are described. β- ketophosphonates were designed as pyrophosphate bioisosteres and were investigated as UDP-GlcNAc mimics. The developed st

Synthesis of a ss-ketophosphonate bioisostere of UDP-N- acetylglucosamine

A concise route to a new β-ketophosphonate analog of glycosyl nucleotides is described. Such a diphosphate bioisostere is a stable mimic of enzyme substrates involved, in peptidoglycan biosynthesis and will be the starting point for the development of new