1182348-97-5Relevant articles and documents
Drug design, in vitro pharmacology, and structure-activity relationships of 3-acylamino-2-aminopropionic acid derivatives, a novel class of partial agonists at the glycine site on the N-methyl-D-aspartate (NMDA) receptor complex
Urwyler, Stephan,Floersheim, Philipp,Roy, Bernard L.,Koller, Manuel
supporting information; experimental part, p. 5093 - 5107 (2010/03/02)
Retaining agonistic activity at the glycine coagonist site of the NMDA receptor in molecules derived from glycine or D-serine has proven to be difficult because in the vicinity of the α-amino acid group little substitution is tolerated. We have solved thi
