118270-06-7Relevant articles and documents
Sequential regio and chemoselective cross-coupling reactions by means of O6-tri-isopropylsulfonate of 4-bromo-pyridazine 3,6-dione
de Araújo-Júnior, Jo?o X.,Schmitt, Martine,Benderitter, Pascal,Bourguignon, Jean-Jacques
, p. 6125 - 6128 (2007/10/03)
Regioselective desymmetrization of 4-substituted pyridazin-3,6-diones using sterically hindered 2,4,6-triisopropylphenyl-sulfonylchloride allowed efficient sequential palladium cross-coupling reactions.
3-Aminopyridazine derivatives with atypical antidepressant, serotonergic, and dopaminergic activities
Wermuth,Schlewer,Bourguignon,Maghioros,Bouchet,Moire,Kan,Worms,Biziere
, p. 528 - 537 (2007/10/02)
Minaprine [3[(β-morpholinoethyl)amino]4-methyl-6-phenylpyridazine dihydrochloride] is active in most animal models of depression and exhibits in vivo a dual dopaminomimetic and serotoninomimetic activity profile. In an attempt to dissociate these two effe