118325-24-9Relevant academic research and scientific papers
Mannosylated saponins based on oleanolic and glycyrrhizic acids. Towards synthetic colloidal antigen delivery systems
Daines, Alison M.,Greatrex, Ben W.,Hayman, Colin M.,Hook, Sarah M.,McBurney, Warren T.,Rades, Thomas,Rendle, Phillip M.,Sims, Ian M.
experimental part, p. 5207 - 5218 (2009/12/01)
Immunostimulatory saponin based colloidal antigen delivery systems show promise as adjuvants for subunit vaccines. For this reason, allyl oleanolate was glycosylated at the 3-position using trichloroacetimidate donors to give monodesmodic saponins followi
Saponin and sapogenol. XLVII. On the constituents of the roots of Glycyrrhiza uralensis Fisher from Northeastern China (1). Licorice-saponins A3, B2, and C2
Kitagawa,Hori,Taniyama,Zhou,Yoshikawa
, p. 43 - 49 (2007/10/02)
From the air-dried root of Glycyrrhiza uralensis, collected in the northeastern part of China, ten new oleanane-type triterpene oligoglycosides were isolated together with glycyrrhizin (1) and several known flavonoids. Among the newly isolated triterpene oligoglycosides, the chemical structures of licorice-saponin A3 (2), licorice-saponin B2 (3), and licorice-saponin C2 (4) have been determined, on the basis of chemical and physicochemical evidence, to be expressed as 30-O-β-D-glucopyranosylglycyrrhizin, 11-deoxo-glycyrrhizin, and 3-O-[β-D-glucuronopyranosyl(1→2)-β-D-glucuronopyranosyl]oleana-11,1 3(18)-dien-30-oic acid, respectively. During the course of these studies, facile conversions from glycyrrhizin (1) to licorice-saponins A3 (2), B2 (3), and C2 (4) have been accomplished.
