118329-60-5Relevant academic research and scientific papers
1-tertiary-alkyl-substituted naphthyridine carboxylic acid antibacterial agents
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, (2008/06/13)
There are disclosed new naphthyridine- and quinoline-carboxylic acids having a 1-tertiary-alkyl substituent, compositions containing them, and their use in treating bacterial infections in warm-blooded animals. Also disclosed are novel amines and intermediates used in the preparation of the naphthyridine- and quinoline-carboxylic acids.
Fluoronaphthyridines and Quinolones as Antibacterial Agents. 2. Synthesis and Structure-Activity Relationships of New 1-tert-Butyl 7-Substituted Derivatives
Bouzard, D.,Di Cesare, P.,Essiz, M.,Jacquet, J. P.,Kiechel, J. R.,et al.
, p. 1344 - 1352 (2007/10/02)
A number of 7-substituted-1-tert-butyl-6-fluoroquinolone-3-carboxylic acids and 7-substituted-1-tert-butyl-6-fluoro-1,8-naphthyridine-3-carboxylic acids have been prepared and tested for antibacterial activities.Among those the 7-aminopyrrolidinyl 20b and
