1183577-37-8

Basic information

• Product Name: [methyl(phenethyl)sulfamoyl]acetic acid
• Synonyms: [methyl(phenethyl)sulfamoyl]acetic acid
• CAS NO: 1183577-37-8
• Molecular Weight: 257.31
• Mol File: 1183577-37-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [methyl(phenethyl)sulfamoyl]acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: [methyl(phenethyl)sulfamoyl]acetic acid(1183577-37-8)
• EPA Substance Registry System: [methyl(phenethyl)sulfamoyl]acetic acid(1183577-37-8)

Safety Data

• Hazardous Substances Data: 1183577-37-8(Hazardous Substances Data)

Upstream product

• 233283-81-3 2-[methyl(phenethyl)sulfamoyl]acetic acid methyl ester 

Downstream Products

• 1449784-13-7 (E)-2-(3,4-dihydroxyphenyl)ethenesulfonic acid N-methyl-N-(phenethyl)amide 

Relevant articles and documents

Design, synthesis and pharmacological evaluation of (E)-3,4-dihydroxy styryl sulfonamides derivatives as multifunctional neuroprotective agents against oxidative and inflammatory injury

A novel class of (E)-3,4-dihydroxy styryl sulfonamides and their 3,4-diacetylated derivatives as caffeic acid phenethyl ester (CAPE) analogs was designed and prepared for improving stability and solubility of the lead compound. Their neuroprotective properties were assessed by several models. The results showed that target compounds displayed positive free radical quenching abilities, superior to that of CAPE. Compounds 6j-k and 7j-k demonstrated remarkable protection effects against damage induced by hydrogen peroxide which were apparently stronger than that of CAPE. Most of target compounds could inhibit nitric oxide production. Additionally, target compounds showed high blood-brain barrier permeability.