118371-41-8

Basic information

• Product Name: Dodecahydro-10,13-dimethyl-2H-cyclopenta[a]phenanthren-3(4H,9H,14H)-one
• Synonyms: Dodecahydro-10,13-dimethyl-2H-cyclopenta[a]phenanthren-3(4H,9H,14H)-one;Androstan-3-one
• CAS NO: 118371-41-8
• Molecular Formula: C19H30O
• Molecular Weight: 274.45
• Mol File: 118371-41-8.mol
• Article Data: 12

Chemical Properties

• Melting Point: 103-104 ºC
• Boiling Point: 368.5 °C at 760 mmHg
• Flash Point: 168.7 °C
• Appearance: /
• Density: 1.014
• Vapor Pressure: 1.27E-05mmHg at 25°C
• Refractive Index: 1.517
• CAS DataBase Reference: Dodecahydro-10,13-dimethyl-2H-cyclopenta[a]phenanthren-3(4H,9H,14H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: Dodecahydro-10,13-dimethyl-2H-cyclopenta[a]phenanthren-3(4H,9H,14H)-one(118371-41-8)
• EPA Substance Registry System: Dodecahydro-10,13-dimethyl-2H-cyclopenta[a]phenanthren-3(4H,9H,14H)-one(118371-41-8)

Safety Data

• Hazardous Substances Data: 118371-41-8(Hazardous Substances Data)

Usage

General Description

Dodecahydro-10,13-dimethyl-2H-cyclopenta[a]phenanthren-3(4H,9H,14H)-one is a chemical compound with a complex molecular structure. It belongs to the group of cyclopenta[a]phenanthrenes and is a ketone derivative. This chemical is a steroid and is commonly found in plants, animals, and fungi. It is also used in pharmaceuticals and research as a starting material for the synthesis of other compounds. The chemical may have potential applications in medicine and biology due to its structural features and biological activities. Further research is needed to fully understand the properties and potential uses of this compound.

InChI:InChI=1/C19H30O/c1-18-9-3-4-16(18)15-6-5-13-12-14(20)7-11-19(13,2)17(15)8-10-18/h13,15-17H,3-12H2,1-2H3/t13-,15-,16-,17-,18-,19-/m0/s1

Upstream product

• 3248-10-0 (5S,8S,9S,10S,13S,14S)-10,13-dimethyl-4,5,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one 
• 1224-93-7 5α-androstan-3β-ol 
• 64-19-7 acetic acid 
• 53-43-0 dehydroepiandrosterone 
• 1476-64-8 androst-5-en-3β-ol 
• 4732-78-9 (3β,5α,13β)-3-hydroxy-18-norandrostan-17-one 
• 396079-66-6 17α-benzoyloxy-5β-androstanone-(3) 
• 36025-82-8 3-oxoandrost-4-en-17α-yl benzoate 
• 53-42-9 Etiocholanolone 
• 64-17-5 ethanol 
• 52225-35-1 5β-androst-16-en-3-one 
• 2872-90-4 4-androsten-3-one 
• 1224-92-6 5beta-Androstan-3alpha-ol 
• 481-29-8 Epiandrosterone 

Downstream Products

• 25788-17-4 5α-Androstan-12,15-dion 
• 4642-58-4 3--5α-androst-2-en 
• 4642-51-7 3--5α-androst-2-en 
• 4678-96-0 3'-acetyl-(3ξN,5α)-spiro[androstane-3,2'-thiazolidine] 
• 26156-06-9 2-p-Methoxybenzyliden-5α-androstan-3β-ol 
• 25825-89-2 2-p-Methoxybenzyliden-5α-androst-3en 
• 78514-54-2 Benzoic acid (5S,8S,9S,10S,13S,14S)-10,13-dimethyl-3-phenylsulfanylmethyl-hexadecahydro-cyclopenta[a]phenanthren-3-yl ester 
• 81916-98-5 androstane-3β-ylmethyl toluene-p-sulphonate 
• 81916-97-4 androstane-3α-ylmethyl toluene-p-sulphonate 
• 3090-99-1 3-ketoandrosta-1,4-diene 
• 69809-13-8 2α-Phenylseleno-5α-androstan-3-on 
• 17287-99-9 2-(4-Methoxybenzyliden)-5α-androstan-3-on 
• 3248-10-0 (5S,8S,9S,10S,13S,14S)-10,13-dimethyl-4,5,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one 
• 2872-90-4 4-androsten-3-one 

Relevant articles and documents

HUMAN GHRELIN O-ACYL TRANSFERASE INHIBITORS

A class of cyanosteroid compounds that efficiently inhibit ghrelin acylation by ghrelin O-acyltransferase. The compounds have a steroid scaffold with α,β-unsaturated ketone in the A ring position such an a-cyanoenone. Exemplary compounds include (5S,8S,9S,10S, 13S,14S)-10,13-dimethyl-3-oxo-4,5,6,7,8,9,10,11,12,13,14,15,16,17- tetradecahydro-3H-cyclopenta[a]phenanthrene-2-carbonitrile.

Novel and efficient synthesis and antifungal evaluation of 2,3-functionalized cholestane and androstane derivatives

Synthetic modifications of cholesterol and other traditional steroid molecules have become a promising area for the exploration and development of novel antifungal agents, especially with respect to the development of fatty-acid esters of steroids. In addition, 2,3-functionalized steroids are also compounds with potentially interesting biological properties and proper functionalization of 2,3-steroids can lead to the development of efficient syntheses of building blocks for novel fatty-acid esters of steroids. In this Letter, we outline a novel and efficient approach to the synthesis of 2,3-functionalized cholestane and androstane derivatives and present their promising preliminary antifungal activities against a number of fungal species.