118408-48-3Relevant academic research and scientific papers
Preparation of Nitroalkenes: Substitution Reaction via Addition-Elimination Using β-Nitrovinyl Sulfoxides
Nobe, Manabu,Itoh, Akichika,Nishide, Kiyoharu,Abe, Hitoshi,Kawabata, Takeo,et al.
, p. 1119 - 1124 (2007/10/02)
Nitroalkenes were prepared by the substitution reaction of β-nitrovinyl sulfides and sulfoxides with a variety of carbon nucleophiles (i.e. alkylmetal reagents and enolates of carbonyl compounds), via an addition-elimination sequence.The sulfoxide as a leaving group was suitable for the reaction with an enolate of carbonyl compounds.This method was useful for the synthesis of nitroalkenes .
Addition-elimination strategy for asymmetric induction: A chiral sulfoxide as a leaving group
Fuji,Node,Abe,Itoh,Masaki,Shiro
, p. 2419 - 2422 (2007/10/02)
The reaction of β-nitro-α,β-unsaturated sulfoxide 7 with δ-lactam enolates 11 - 15 afforded 20 - 24, respectively, in good chemical yields with high enantiomeric excesses.
