118430-74-3

Usage

Uses

Used in Organic Synthesis:
3-CYCLOPROPYL-1-METHYL-1H-PYRAZOL-5-AMINE is used as a key intermediate in the synthesis of a variety of organic compounds, contributing to the development of new chemical entities with potential applications in various fields.
Used in Pharmaceutical Industry:
Although its specific uses and effects are not widely documented, 3-CYCLOPROPYL-1-METHYL-1H-PYRAZOL-5-AMINE is known to possess pharmacological activity. It is used as a potential active pharmaceutical ingredient for the development of new drugs, targeting various therapeutic areas.
It is important to handle and use 3-CYCLOPROPYL-1-METHYL-1H-PYRAZOL-5-AMINE in accordance with relevant safety guidelines and regulations to ensure its safe application in research and development processes.

InChI:InChI=1/C7H11N3/c1-10-7(8)4-6(9-10)5-2-3-5/h4-5H,2-3,8H2,1H3

Upstream product

• 118431-88-2 3-cyclopropyl-3-oxo-propionitrile 
• 60-34-4 methylhydrazine 

Downstream Products

• 1430094-10-2 C₃₀H₂₄Cl₂N₆ 
• 1430094-12-4 C₃₀H₂₄Br₂N₆ 
• 1430094-15-7 C₃₂H₃₀N₆O₂ 
• 1610600-33-3 (3-cyclopropyl-1-methyl-6-phenyl-5-(p-tolylamino)-1H-pyrazolo[3,4-b]pyridin-4-yl)(phenyl)methanone 
• 1610600-32-2 (5-((4-chlorophenyl)amino)-3-cyclopropyl-1-methyl-6-phenyl-1H-pyrazolo[3,4-b]pyridin-4-yl)(phenyl)methanone 
• 1610600-39-9 (4-chlorophenyl)(6-(4-chlorophenyl)-3-cyclopropyl-1-methyl-5-(p-tolylamino)-1H-pyrazolo[3,4-b]pyridin-4-yl)methanone 
• 1610600-38-8 (4-chlorophenyl)(6-(4-chlorophenyl)-5-((4-chlorophenyl)amino)-3-cyclopropyl-1-methyl-1H-pyrazolo[3,4-b]pyridin-4-yl)methanone 
• 1610600-37-7 (3-cyclopropyl-6-(4-methoxyphenyl)-1-methyl-5-(p-tolylamino)-1H-pyrazolo[3,4-b]pyridin-4-yl)(4-methoxyphenyl)methanone 
• 1610600-35-5 (4-bromophenyl)(6-(4-bromophenyl)-3-cyclopropyl-1-methyl-5-(p-tolylamino)-1H-pyrazolo[3,4-b]pyridin-4-yl)methanone 
• 1610600-36-6 (5-((4-chlorophenyl)amino)-3-cyclopropyl-6-(4-methoxyphenyl)-1-methyl-1H-pyrazolo[3,4-b]pyridin-4-yl)(4-methoxyphenyl)methanone 
• 1610600-34-4 (4-bromophenyl)(6-(4-bromophenyl)-5-((4-bromophenyl)amino)-3-cyclopropyl-1-methyl-1H-pyrazolo[3,4-b]pyridin-4-yl)methanone 
• 1610600-40-2 (3-cyclopropyl-5-((4-methoxyphenyl)amino)-1-methyl-6-(4-nitrophenyl)-1H-pyrazolo[3,4-b]pyridin-4-yl)(4-nitrophenyl)methanone 

Relevant academic research and scientific papers

PROCESS FOR THE PREPARATION OF SUBSTITUTED PYRAZOLES

The invention relates to an alternative process for the preparation of substituted 5-amino-pyrazoles, in which a carbonyl compound is reacted with a hydrazine derivative and cyanogen chloride to give an N-cyanohydrazone which is cyclized in the presence of a strong base.

QUINAZOLINE DERIVATIVES

The invention concerns quinazoline derivatives of Formula (I) or a pharmaceutically-acceptable salt, solvate or pro-drug thereof, wherein each of X1, p, R1, q, R2, R3, R4, R5, Ring A, r and R6 has any of the meanings defined hereinbefore in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use in the treatment of cell proliferative disorders or in the treatment of disease states associated with angiogenesis and/or vascular permeability.