1184350-70-6Relevant articles and documents
The benzyne aza-claisen reaction
Cant, Alastair A.,Bertrand, Guillaume H. V.,Henderson, Jaclyn L.,Roberts, Lee,Greaney, Michael F.
supporting information; experimental part, p. 5199 - 5202 (2009/12/27)
Adding an aryne to a tertiary allylamine affords oallylaniline products of an aza-Claisen rearrangement. The aryne simultaneously provides the π component for the rearrangement and the quaternization event that lowers the activation energy for the sigmatr