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1H-Benzimidazole-2-carboxaldehyde,1-(fluoromethyl)-(9CI) is a chemical compound characterized by a benzimidazole ring, a carboxaldehyde group, and a fluoromethyl substituent. With the molecular formula C9H6FN2O, this compound serves as a versatile intermediate in synthetic organic chemistry, particularly for the production of pharmaceuticals and agrochemicals. Its unique structural features, including the fluoromethyl group, make it a valuable building block in the preparation of fluorinated compounds, which are significant in drug discovery and development. 1H-Benzimidazole-2-carboxaldehyde,1-(fluoromethyl)-(9CI) also holds potential in material science and medicinal chemistry, highlighting its importance as a chemical intermediate with diverse applications.

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  • 118469-08-2 Structure
  • Basic information

    1. Product Name: 1H-Benzimidazole-2-carboxaldehyde,1-(fluoromethyl)-(9CI)
    2. Synonyms: 1H-Benzimidazole-2-carboxaldehyde,1-(fluoromethyl)-(9CI);1H-Benzimidazole-2-carboxaldehyde,1-(fluoromethyl)-;1-(Fluoromethyl)-1H-benzimidazole-2-carboxaldehyde
    3. CAS NO:118469-08-2
    4. Molecular Formula: C9H7FN2O
    5. Molecular Weight: 178.165
    6. EINECS: N/A
    7. Product Categories: BENZIMIDAZOLE
    8. Mol File: 118469-08-2.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 341.9°C at 760 mmHg
    3. Flash Point: 160.6°C
    4. Appearance: /
    5. Density: 1.30±0.1 g/cm3 (20 ºC 760 Torr)
    6. Vapor Pressure: 7.78E-05mmHg at 25°C
    7. Refractive Index: 1.601
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: 1H-Benzimidazole-2-carboxaldehyde,1-(fluoromethyl)-(9CI)(CAS DataBase Reference)
    11. NIST Chemistry Reference: 1H-Benzimidazole-2-carboxaldehyde,1-(fluoromethyl)-(9CI)(118469-08-2)
    12. EPA Substance Registry System: 1H-Benzimidazole-2-carboxaldehyde,1-(fluoromethyl)-(9CI)(118469-08-2)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 118469-08-2(Hazardous Substances Data)

118469-08-2 Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
1H-Benzimidazole-2-carboxaldehyde,1-(fluoromethyl)-(9CI) is used as a reagent and intermediate for the synthesis of various pharmaceuticals and agrochemicals. Its unique structure and fluoromethyl group contribute to the development of new and improved compounds with enhanced properties and efficacy.
Used in Drug Discovery and Development:
As a building block for the preparation of fluorinated compounds, 1H-Benzimidazole-2-carboxaldehyde,1-(fluoromethyl)-(9CI) is utilized in drug discovery and development. The incorporation of fluorine atoms into drug molecules can significantly influence their pharmacokinetic and pharmacodynamic properties, leading to improved therapeutic outcomes.
Used in Material Science:
Due to its unique structural features, 1H-Benzimidazole-2-carboxaldehyde,1-(fluoromethyl)-(9CI) may have potential applications in material science. Its properties can be harnessed to develop new materials with specific characteristics, such as enhanced stability, reactivity, or selectivity.
Used in Medicinal Chemistry:
1H-Benzimidazole-2-carboxaldehyde,1-(fluoromethyl)-(9CI)'s structural features also make it a promising candidate for applications in medicinal chemistry. It can be used to design and synthesize new drug molecules with improved binding affinity, selectivity, and therapeutic potential.

Check Digit Verification of cas no

The CAS Registry Mumber 118469-08-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,8,4,6 and 9 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 118469-08:
(8*1)+(7*1)+(6*8)+(5*4)+(4*6)+(3*9)+(2*0)+(1*8)=142
142 % 10 = 2
So 118469-08-2 is a valid CAS Registry Number.
InChI:InChI=1/C9H7FN2O/c10-6-12-8-4-2-1-3-7(8)11-9(12)5-13/h1-5H,6H2

118469-08-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(fluoromethyl)benzimidazole-2-carbaldehyde

1.2 Other means of identification

Product number -
Other names 1-(Fluoromethyl)-1H-benzo[d]imidazole-2-carbaldehyde

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:118469-08-2 SDS

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