118469-75-3

Basic information

• Product Name: Phenol, 4-tetradecyl-, acetate
• CAS NO: 118469-75-3
• Molecular Formula: C22H36O2
• Molecular Weight: 332.527
• Mol File: 118469-75-3.mol

Chemical Properties

• CAS DataBase Reference: Phenol, 4-tetradecyl-, acetate(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 4-tetradecyl-, acetate(118469-75-3)
• EPA Substance Registry System: Phenol, 4-tetradecyl-, acetate(118469-75-3)

Safety Data

• Hazardous Substances Data: 118469-75-3(Hazardous Substances Data)

Upstream product

• 25401-89-2 4-n-tetradecylphenol 
• 108-24-7 acetic anhydride 

Downstream Products

• 140466-53-1 Phosphoric acid 2-acetyl-4-tetradecyl-phenyl ester 3-bromomethyl-phenyl ester 
• 140467-00-1 Phosphoric acid 3-bromomethyl-phenyl ester 2-ethyl-4-tetradecyl-phenyl ester 
• 118469-77-5 2-ethyl-4-tetradecylphenol 
• 118469-76-4 1-(2-hydroxy-5-tetradecylphenyl)ethanone 

Relevant articles and documents

Analogues of Platelet Activating Factor. 6. Mono- and Bis-Aryl Phosphate Antagonists of Platelet Activating Factor

A series of aryl phosphoglyceride (3, 19-61) and bis-aryl phosphate (67-135) antagonists of platelet activating factor (PAF) were prepared.A group of four bifunctional phosphorus reagents (5a-c and 7) were developed that allowed the preparation of these aryl phosphates in which the position of aromatic substitution can be varied.These compounds were examined for their ability to inhibit PAF-induced platelet aggregation of rabbit platelets.Selected compounds were also evaluated for their ability to displace PAF from its receptor on rabbit platelets.These in vitro data were compared to similar data obtained for a number of known PAF antagonists.The compounds were evaluated in vivo, in both the mouse and rabbit, for their ability to prevent death induced by a lethal challenge of PAF.The relationships between the biological activity and the nature, lipophilicity, and position of substituents of the aromatic rings were studied.Compound 105 (CL 184005) has been selected to undergo further development as a potential therapeutic agent for the treatment of septic shock in man.

SULFUR INHIBITORS OF PHOSPHOLIPASE A-Z

Phospholipase A2 inhibitors having the formula wherein R" is a C2-C20 alkyl group, R1" is a C1-C4 alkyl group, y is an integer from 2 to 10, and J- is a pharmaceutically acceptable anion, are described

Antihypertensive phosphate derivatives

Antihypertensive phosphate derivatives having the following formula are described: STR1 wherein X is selected from one or more of: (a) C1 -C24 branched or straight chain alkyl; (b) C1 -C24 branched or straight chain alkoxy; (c) STR2 wherein n and m are integers from 0 to 25 and the sum of n and m is less than or equal to 25; phenyl; substituted phenyl wherein the substituents are selected from the group consisting of C1 -C20 branched or straight chain alkyl, C1 -C20 branched or straight chain alkoxy, halogen, trifluoromethyl, phenyl, and substituted phenyl, phenoxy; and substituted phenoxy, wherein the substituents are selected from the group consisting of C1 -C20 branched or straight chain alkyl, halogen, trifluoromethyl, phenyl and substituted phenyl; Q is selected from the group consisting of: STR3 wherein R1 is selected from the group consisting of hydrogen, C1 -C4 branched or straight chain alkyl, C1 -C4 branched or straight chain alkoxy and C1 -C4 branched or straight chain alkylamino and wherein R3 is C1 -C4 alkyl, with the proviso that when Q is STR4 then R1 is C1 -C4 branched or straight chain alkyl; T is a bivalent radical selected from the group consisting of --(CHR)p -- and STR5 wherein p is an integer from 1 to 15, the moiety --(CHR)p -- represents an alkylene chain substituted at any position with one or more C1 -C10 alkyl groups or phenyl groups, and the moiety STR6 is bound with the oxygen atom attached directly to the aromatic ring; and Z is STR7 wherein R2 is hydrogen or C1 -C4 branched or straight chain alkyl and q is an interger from 4 to 7; in either the racemic or optically active forms.