118487-01-7Relevant academic research and scientific papers
A new, highly stereoselective synthesis of β-unsubstituted (Z)-γ-alkylidene-butenolides using bromine as a removable stereocontrol element
Boukouvalas, John,Beltrán, Paola P.,Lachance, Nicolas,C?té, Sébastien,Maltais, Fran?ois,Pouliot, Martin
, p. 219 - 222 (2007/10/03)
Several β-unsubstituted (Z)-γ-alkylidenebutenolides have been prepared in highly stereocontrolled fashion by implementing a steric directing group stratagem in the vinylogous aldol condensation of butenolides with aldehydes. Applications to the synthesis of the antitumor heptene (S)-melodorinol and a thiophenelactone from Chamaemelum nobile L. are described. Georg Thieme Verlag Stuttgart.
Oxidative Substitution Reactions of Organostannyl Compounds with Lead Tetraacetate. A Convenient Route to 5-Alkylidene-2(5H)-furanones
Yamamoto, Makoto,Munakata, Hiroshi,Kishikawa, Keiki,Kohmoto, Shigeo,Yamada, Kazutoshi
, p. 2366 - 2370 (2007/10/02)
5-Substituted 2-tributylstannylfurans which were synthesized by the reaction of corresponding 5-substituted 2-lithiofurans with tribitylstannyl chloride, were treated with two equimolar amounts of lead tetraacetate at room temperature to give corresponding 5-substituted 5-acetoxy-2(5H)-furanones in good yields.The 5-acetoxy-2(5H)-furanone was heated at 80 deg C in acetic acid-acetic anhydride containing a catalytic amount of concentrated sulfuric acid to give 5-alkylidene-2(5H)-furanone in moderate yield.
Oxidative Substitution Reactions of Organotin Compounds with Lead Tetra-acetate
Yamamoto, Makoto,Izukawa, Hiroyoshi,Saiki, Masaru,Yamada, Kazutoshi
, p. 560 - 561 (2007/10/02)
A new oxidative substitution reaction where an organotin group is replaced by an acetoxy group has been investigated; this reaction has been successfully applied to the synthesis of 4-ylidenebutenolides.
