118492-81-2 Usage
General Description
(8)S-HEPE, also known as 8(S)-hydroxyeicosapentaenoic acid, is a type of fatty acid derived from eicosapentaenoic acid (EPA), which is an omega-3 fatty acid found in fish oil. It is a specialized pro-resolving mediator (SPM) that plays a key role in the resolution of inflammation and the regulation of immune responses. (8)S-HEPE has been shown to have anti-inflammatory and pro-resolving effects in various disease models, such as arthritis, colitis, and asthma. It is believed to exert its beneficial effects by promoting the clearance of inflammatory cells and the resolution of inflammation, making it a promising therapeutic target for the treatment of inflammatory and immune-mediated disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 118492-81-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,8,4,9 and 2 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 118492-81:
(8*1)+(7*1)+(6*8)+(5*4)+(4*9)+(3*2)+(2*8)+(1*1)=142
142 % 10 = 2
So 118492-81-2 is a valid CAS Registry Number.
118492-81-2Relevant articles and documents
Synthesis of 8-HEPE and 10-HDoHE in both (R)- and (S)-Forms via Wittig Reactions with COOH-Ylides
Suganuma, Yuta,Saito, Shun,Kobayashi, Yuichi
, p. 338 - 342 (2019)
Wittig reactions using carboxy (CO 2 H) ylides derived from a carboxylic phosphonium salt and NaN(TMS) 2 (NaHMDS) in a 1:1 ratio were applied to the synthesis of 8-HEPE and 10-HDoHE, which are metabolites of eicosapentaenoic acid and
