118492-81-2 Usage
Uses
Used in Pharmaceutical Industry:
(8)S-HEPE is used as an anti-inflammatory and pro-resolving agent for its ability to promote the clearance of inflammatory cells and the resolution of inflammation, making it a promising therapeutic target for the treatment of inflammatory and immune-mediated disorders.
Used in Arthritis Treatment:
(8)S-HEPE is used as a therapeutic agent for arthritis, where it helps in reducing inflammation and promoting the resolution of the disease.
Used in Colitis Treatment:
(8)S-HEPE is used as a therapeutic agent for colitis, where it exhibits anti-inflammatory effects and contributes to the resolution of the inflammatory process in the colon.
Used in Asthma Treatment:
(8)S-HEPE is used as a therapeutic agent for asthma, where it helps in reducing airway inflammation and improving respiratory function by promoting the resolution of inflammation.
Check Digit Verification of cas no
The CAS Registry Mumber 118492-81-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,8,4,9 and 2 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 118492-81:
(8*1)+(7*1)+(6*8)+(5*4)+(4*9)+(3*2)+(2*8)+(1*1)=142
142 % 10 = 2
So 118492-81-2 is a valid CAS Registry Number.
118492-81-2Relevant articles and documents
Synthesis of 8-HEPE and 10-HDoHE in both (R)- and (S)-Forms via Wittig Reactions with COOH-Ylides
Suganuma, Yuta,Saito, Shun,Kobayashi, Yuichi
, p. 338 - 342 (2019)
Wittig reactions using carboxy (CO 2 H) ylides derived from a carboxylic phosphonium salt and NaN(TMS) 2 (NaHMDS) in a 1:1 ratio were applied to the synthesis of 8-HEPE and 10-HDoHE, which are metabolites of eicosapentaenoic acid and