118495-40-2Relevant academic research and scientific papers
HYDROXYLATED PIPERIDINES: SYNTHESIS OF 1,5-ALKYLIMINO-1,5-DIDEOXY DERIVATIVES OF XYLITOL, D- AND L-ARABINITOL, AND RIBITOL
McCaig, Avril E.,Chomier, Berangere,Wightman, Richard H.
, p. 397 - 408 (2007/10/02)
Direct routes are reported for the synthesis of N-propyl, N-butyl and N-pentyl-1,5-dideoxy-1,5-iminoxylitol (7a,b,c), the analogous derivatives (8a,b,c, and 9a,b,c) of 1,5-dideoxy-1,5-imino-D- and -L-arabinitol, and of N-propyl-1,5-dideoxy-1,5-iminoribito
The use of triphenylphosphine/diethyl azodicarboxylate (DEAD) for the cyclization of 1,4- and 1,5-amino alcohols
Bernotas,Cube
, p. 161 - 164 (2007/10/02)
Application of the Mitsunobu reagent to the cyclization of 1,4- and 1,5-amino alcohols provided an assortment of azacycles in good to excellent yield.
A new family of five-carbon iminoalditols which are potent glycosidase inhibitors
Bernotas, Ronald C.,Papandreou, George,Urbach, Jonathan,Oanem, Bruce
, p. 3393 - 3396 (2007/10/02)
The synthesis of 1,5-dideoxy-1,5-imino-D-xylitol 2 (and the enantiomeric iminoalditols 3 and 4) is described. Alditol 2 compares favorably with 1-deoxynojirimycin 1 as a potent inhibitor of β-glucosidase.
