1185133-81-6 Usage
Description
Flurbiprofen-d3 is intended for use as an internal standard for the quantification of flurbiprofen (Item Nos. 70250 | 10004207 | 70255) by GC- or LC-MS. Flurbiprofen is a non-selective COX inhibitor (IC50s = 0.04 and 0.51 μM for COX-1 and COX-2, respectively). In vivo, flurbiprofen (0.3-4.8 mg/kg, p.o.) reduces carrageenan-induced hind paw edema and yeast-induced fever in rats. Flurbiprofen reduces plasma fibrinogen levels and arthritic score in a rat model of adjuvant-induced arthritis. It also reduces tumor weight and prostaglandin production and increases survival in a WHT-NC mouse xenograft model when administered at a dose of 5 mg/kg. Formulations containing flurbiprofen have been used to manage pain and inflammation associated with arthritis.
Chemical Properties
White Solid
Uses
Different sources of media describe the Uses of 1185133-81-6 differently. You can refer to the following data:
1. An Isotopically labeled analog of Flurbiprofe
2. An isotopically labelled analog of Flurbiprofen (F598700).
Check Digit Verification of cas no
The CAS Registry Mumber 1185133-81-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,8,5,1,3 and 3 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1185133-81:
(9*1)+(8*1)+(7*8)+(6*5)+(5*1)+(4*3)+(3*3)+(2*8)+(1*1)=146
146 % 10 = 6
So 1185133-81-6 is a valid CAS Registry Number.
