1185143-77-4

Basic information

• Product Name: S-{[(4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)-8-(2-fluoro-4-methoxyphenyl)-5-hydroxy-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,9a,10,10a,10b,11,12-dodecahydro-6bH-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-6b-yl]carbonyl} dimethylthiocarbamate
• Synonyms: S-{[(4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)-8-(2-fluoro-4-methoxyphenyl)-5-hydroxy-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,9a,10,10a,10b,11,12-dodecahydro-6bH-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-6b-yl]carbonyl} dimethylthiocarbamate
• CAS NO: 1185143-77-4
• Molecular Weight: 585.694
• Mol File: 1185143-77-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: S-{[(4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)-8-(2-fluoro-4-methoxyphenyl)-5-hydroxy-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,9a,10,10a,10b,11,12-dodecahydro-6bH-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-6b-yl]carbonyl} dimethylthiocarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: S-{[(4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)-8-(2-fluoro-4-methoxyphenyl)-5-hydroxy-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,9a,10,10a,10b,11,12-dodecahydro-6bH-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-6b-yl]carbonyl} dimethylthiocarbamate(1185143-77-4)
• EPA Substance Registry System: S-{[(4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)-8-(2-fluoro-4-methoxyphenyl)-5-hydroxy-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,9a,10,10a,10b,11,12-dodecahydro-6bH-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-6b-yl]carbonyl} dimethylthiocarbamate(1185143-77-4)

Safety Data

• Hazardous Substances Data: 1185143-77-4(Hazardous Substances Data)

Upstream product

• 13951-70-7 desonide 
• 1185143-75-2 (8S,9S,10R,11S,13S,14S,16R,17S)-11,16,17-trihydroxy-10,13-dimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylic acid 
• 331-64-6 2-fluoro-4-methoxy-benzaldehyde 
• 1185143-78-5 (4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)-8-(2-fluoro-4-methoxyphenyl)-5-hydroxy-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,9a,10,10a,10b,11,12-dodecahydro-6bH-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxole-6b-carboxylic acid 
• 16420-13-6 N,N-Dimethylthiocarbamoyl chloride 

Relevant articles and documents

16 ALPHA, 17 ALPA-ACETAL GLUCOCORTICOSTEROIDAL DERIVATIVES AND THEIR USE

The present invention provides compounds of formula (I) wherein R1, R2, R3, R4, R5 and R6 are as defined in the specification, a process for their preparation, pharmaceutical compositions containing them and their use in therapy.