1185143-90-1

Basic information

• Product Name: C₂₂H₂₇⁽²⁾H₃N₂O₂S
• CAS NO: 1185143-90-1
• Molecular Weight: 389.535
• Mol File: 1185143-90-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₂H₂₇⁽²⁾H₃N₂O₂S(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₂H₂₇⁽²⁾H₃N₂O₂S(1185143-90-1)
• EPA Substance Registry System: C₂₂H₂₇⁽²⁾H₃N₂O₂S(1185143-90-1)

Safety Data

• Hazardous Substances Data: 1185143-90-1(Hazardous Substances Data)

Upstream product

• 61380-07-2 2-(thiophen-2-yl)ethyl methanesulfonate 
• 1204688-16-3 N-(4-(d3-methoxymethyl)piperidin-4-yl)-N-phenylpropionamide 

Relevant articles and documents

A facile method for preparation of [2H3]-sufentanil and its metabolites

An improved process for the synthesis of sufentanil with an overall yield of 26% is described. The reactive and high yielding N-debenzylation of the piperidine intermediate 7 using a mixture of Pd/C and Pd(OH)2 was applied to other drug intermediates affording free amines in short reaction times. The deuterium-labeled sufentanil and the metabolite desmethylsufentanil were synthesized applying the optimized process.