1185167-55-8

Basic information

• Product Name: 1-(2-isopropylthiazol-4-yl-N-MethylMethanaMine
• Synonyms: 2-Isopropyl-4(((N-Methyl) aMino)Methyl)thiazole dihydrochloride;1-(2-isopropylthiazol-4-yl)-N-MethylMethanaMine dihydrochloride;N-Methyl-2-(1-Methylethyl)-4-thiazoleMethanaMine dihydrochloride;2-Isopropyl-7-(((N-Methyl)aMino)Methyl)thiozolehydrochloride;N-Methyl-2-(1-Methylethyl)-4-thiazoleMethanaMine;2-Isopropyl-4-(N-MethylaMinoMethyl)thiazole Hydrochloride salt(1：2);4-Thiazolemethanamine, N-methyl-2-(1-methylethyl)-, hydrochloride (1:2);2-ISOPROPYL-4(((N-METHYL) AMINO)METHYL)THIAZOLE 2HCL
• CAS NO: 1185167-55-8
• Molecular Formula: C8H16Cl2N2S
• Molecular Weight: 243.19704
• EINECS: 1592732-453-0
• Mol File: 1185167-55-8.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: DMSO (Slightly), Methanol (Slightly)
• CAS DataBase Reference: 1-(2-isopropylthiazol-4-yl-N-MethylMethanaMine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-isopropylthiazol-4-yl-N-MethylMethanaMine(1185167-55-8)
• EPA Substance Registry System: 1-(2-isopropylthiazol-4-yl-N-MethylMethanaMine(1185167-55-8)

Safety Data

• Hazardous Substances Data: 1185167-55-8(Hazardous Substances Data)

Usage

Description

1-(2-isopropylthiazol-4-yl-N-MethylMethanaMine, commonly known as MPTP, is a chemical compound initially synthesized as a potential analgesic. However, it was later found to be a potent neurotoxin with devastating effects on the brain. MPTP is capable of causing severe and irreversible damage to the dopaminergic system, resulting in symptoms akin to Parkinson's disease. 1-(2-isopropylthiazol-4-yl-N-MethylMethanaMine is metabolized in the brain to form MPP+, which is highly toxic to dopaminergic neurons. Due to its high toxicity, MPTP should be handled with extreme caution.

Uses

Used in Research Applications:
1-(2-isopropylthiazol-4-yl-N-MethylMethanaMine is used as an inducing agent for animal models of Parkinson's disease in research settings. 1-(2-isopropylthiazol-4-yl-N-MethylMethanaMine helps scientists study the progression and mechanisms of the disease, as well as test potential treatments and interventions.
Used in Pharmaceutical Industry:
1-(2-isopropylthiazol-4-yl-N-MethylMethanaMine is used as a reference compound in the development of drugs targeting the dopaminergic system. Understanding the effects of MPTP on dopaminergic neurons aids in the identification of potential therapeutic agents that can protect or restore the function of these neurons in Parkinson's disease.
Used in Toxicology Studies:
1-(2-isopropylthiazol-4-yl-N-MethylMethanaMine is used as a toxicological agent to study the mechanisms of neurotoxicity and the development of strategies to mitigate or prevent the damage caused by similar compounds. This research is crucial for understanding the risks associated with exposure to neurotoxins and developing protective measures.