1185179-33-2
Post Buying Request-
-
Basic information
- Product Name: ACYCLOVIR-D4
- Synonyms: ACYCLOVIR-D4;9-[(2-Hydroxyethoxy-d4)methyl]guanine;Acycloguanosine-d4;2-Amino-1,9-dihydro-9-[(2-hydroxyethoxy-d4)methyl]-6H-Purin-6-one;Acicloftal-d4;Cargosil-d4;Gerpevir-d4;Herpevir-d4
- CAS NO:1185179-33-2
- Molecular Formula: C8H7D4N5O3
- Molecular Weight: 229.23
- EINECS: N/A
- Product Categories: Bases & Related Reagents;Intermediates & Fine Chemicals;Isotope Labeled Compounds;Nucleotides;Pharmaceuticals;Isotope Labelled Compounds
- Mol File: 1185179-33-2.mol
- Article Data: 0
-
Chemical Properties
- Melting Point: >245°C dec.
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: -20°C Freezer
- Solubility: DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
- Stability: Hygroscopic
- CAS DataBase Reference: ACYCLOVIR-D4(CAS DataBase Reference)
- NIST Chemistry Reference: ACYCLOVIR-D4(1185179-33-2)
- EPA Substance Registry System: ACYCLOVIR-D4(1185179-33-2)
-
Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 1185179-33-2(Hazardous Substances Data)
1185179-33-2 Suppliers
Recommended suppliersmore
1185179-33-2 Usage
Description
Acyclovir-d4 is intended for use as an internal standard for the quantification of acyclovir by GC- or LC-MS. Acyclovir is a guanosine analog that has antiviral activity in vitro against the herpes simplex viruses, varicella zoster virus, Epstein-Barr virus, cytomegalovirus, and human herpes virus 6 (ID50s = 0.1-63.1 μM). It diffuses freely into cells and is selectively converted into acyclo-guanosine monophosphate by a virus-specific thymidine kinase. During DNA replication, the phosphorylated form of acyclovir is preferentially incorporated into viral DNA, resulting in premature chain termination and inhibition of further DNA polymerase activity. Acyclovir (5 mg/kg) reduces viral titers in mice infected with the herpes simplex virus-1 (HSV-1) strain SC16.Uses
Different sources of media describe the Uses of 1185179-33-2 differently. You can refer to the following data:1. Acyclovir-d4can be ued as orally active acyclic labelled nucleoside with inhibitory activity towards several herpes viruses.
2. Acyclovir-d4 can be intended for use as an internal standard for the quantification of Acyclovir by GC- or LC-mass spectrometry.
Check Digit Verification of cas no
The CAS Registry Mumber 1185179-33-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,8,5,1,7 and 9 respectively; the second part has 2 digits, 3 and 3 respectively.Calculate Digit Verification of CAS Registry Number 1185179-33:
(9*1)+(8*1)+(7*8)+(6*5)+(5*1)+(4*7)+(3*9)+(2*3)+(1*3)=172
172 % 10 = 2
So 1185179-33-2 is a valid CAS Registry Number.
1185179-33-2Upstream product
1185179-33-2Downstream Products
Post a RFQ
1
What can I do for you?
Get Best Price
Get Best Price for 1185179-33-2
ACYCLOVIR-D4
