118520-85-7Relevant academic research and scientific papers
Generation of 4-iodoisocoumarins through a TBAI-mediated oxidative cyclization of 2-alkynoates
Luo, Jin,He,Chen,Li
, p. 1786 - 1792 (2018/06/18)
A tetra-butylammonium iodide (TBAI)-mediated oxidative iodocyclization of 2-alkynoates for the synthesis of various 4-iodoisocoumarin is described herein, and the reaction is highly efficient and shows broad functional group tolerance. This newly develope
Divergent syntheses of iodinated isobenzofuranones and isochromenones by iodolactonization of 2-alkynylbenzoic acids in ionic liquids
Mancuso, Raffaella,Pomelli, Christian C.,Malafronte, Francesco,Maner, Asif,Marino, Nadia,Chiappe, Cinzia,Gabriele, Bartolo
, p. 4831 - 4841 (2017/07/10)
The regiochemical outcome of the iodolactonization of 2-alkynylbenzoic acids, carried out at 100 °C in ionic liquids (ILs) as unconventional solvents and with molecular iodine as the iodine source, in the absence of external bases, was found to be strongl
Halolactonisation of 2-Alkynylbenzoic Acids
Nagarajan, A.,Balasubramanian, T. R.
, p. 380 (2007/10/02)
Halosubstituted isocoumarins (II) are readily obtained by the halolactonisation reaction of 2-alkynylbenzoic acids with N-halosuccinimides.
Organomercury Mediated Synthesis of Isocoumarins
Nagarajan, A.,Balasubramanian, Tiruvenkat R.
, p. 917 - 919 (2007/10/02)
A facile and convenient synthesis of isocoumarins via an organomercurial route is reported.The synthesis involves reaction of methyl 2-alkynbenzoates with mercuric acetate to give the corresponding isocoumarin mercurials which serve as intermediates to afford the appropriate isocoumarins having substituents as Cl,I,Br,COCH3 etc.
