118525-80-7Relevant academic research and scientific papers
CARBOXYL-MODIFIED AMINO ACIDS AND PEPTIDES: II) A CONVENIENT ROUTE FOR THE SYNTHESIS OF DIFUNCTIONALIZED ENAMINES FROM THIOAMIDES VIA THIOIMINIUM SALTS
Sauve, Gilles,Berre, Nicolas Le,Zacharie, Boulos
, p. 2299 - 2302 (1988)
From thioamides 4, via thioiminium salts 5, various difunctionalized enamines 6 with different electron-withdrawing groups E, E' (E: CN, CO2Me, COR, SO2R, etc; E': CN, CO2Me) are prepared.Application of the methodology, the determination of stereochemistry and degree of racemization of some amino acids are discussed.
