1185295-49-1 Usage
General Description
1-(4-Methylamino-2-piperidin-3-yl-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-6-yl)-ethanone diHCl is a chemical compound consisting of an ethanone group attached to a piperidine ring, a pyrido[4,3-d]pyrimidine ring, and a methylamino group. It is also known as "Apatinib" and is used as an anti-cancer medication, specifically for the treatment of advanced gastric cancer and adenocarcinoma of the gastroesophageal junction. It works by inhibiting the vascular endothelial growth factor receptor-2 (VEGFR-2), which plays a crucial role in tumor angiogenesis and progression. The diHCl form of the compound refers to the presence of two hydrochloride ions, which are added to increase the solubility and stability of the compound. This chemical is typically found in the form of a white to off-white powder and is used primarily in pharmaceutical applications.
Check Digit Verification of cas no
The CAS Registry Mumber 1185295-49-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,8,5,2,9 and 5 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1185295-49:
(9*1)+(8*1)+(7*8)+(6*5)+(5*2)+(4*9)+(3*5)+(2*4)+(1*9)=181
181 % 10 = 1
So 1185295-49-1 is a valid CAS Registry Number.
