1185649-64-2Relevant academic research and scientific papers
Access to 3-(2-Oxoalkyl)-azaspiro[4.5]trienones via Acid-Triggered Oxidative Cascade Reaction through Alkenyl Peroxide Radical Intermediate
Wang, Chang-Sheng,Roisnel, Thierry,Dixneuf, Pierre H.,Soulé, Jean-Fran?ois
supporting information, p. 445 - 450 (2019/01/04)
Azaspiro[4.5]trienones bearing ketone side chains at the 3-position are prepared from N-alkyl-arylpropiolamides and ketones via oxidative 1,2-difunctionalization of alkynes. The cascade sequence starts with the generation of alkenyl peroxide intermediates
Iodocyclization of n-arylpropynamides mediated by hypervalent iodine reagent: Divergent synthesis of iodinated quinolin-2-ones and spiro[4,5]trienones
Zhou, Ying,Zhang, Xiang,Zhang, Yong,Ruan, Linxin,Zhang, Jiacheng,Zhang-Negrerie, Daisy,Du, Yunfei
, p. 150 - 153 (2017/11/27)
PhI(OCOCF3)2 acts as both a nonmetal oxidant and an iodination reagent to trigger iodocyclization of N-arylpropynamides while selectively affording iodinated quinolin-2-ones or the spiro[4,5]trienone skeleton, depending on the substituent pattern. In cases where the Narylpropynamide bears a para-fluorine on the aniline ring, the spiro compound is formed via an exclusive defluorination process; otherwise, the product was quinolin-2-one.
Efficient palladium-catalyzed Suzuki-Miyaura cross-coupling of iodoethynes with arylboronic acids under aerobic conditions
Tang, Jian-Sheng,Xie, Ye-Xiang,Wang, Zhi-Qiang,Li, Jin-Heng
experimental part, p. 2789 - 2795 (2011/10/18)
Ligand-free palladium-catalyzed Suzuki-Miyaura cross-coupling of iodoethynes with arylboronic acids under aerobic conditions has been developed. In the presence of palladium(II) acetate and cesium carbonate, a variety of iodoethynes underwent the Suzuki-M
