1185757-29-2Relevant academic research and scientific papers
Synthesis, structural investigation and antimicrobial properties of macrocyclic zinc(II) complexes with N2O2-donor schiff bases incorporating 1,2,4-triazole ring
Vishwkarma, Arti,Srivastava, Akhilesh K.,Pandey, Om P.,Sengupta, Soumitra K.
, p. 3151 - 3156 (2021/01/06)
A novel series of nano-sized zinc(II) complexes of type [{Zn(M)(H2O)2}(CH3COO-)2] (where M = macrocyclic ligands) has been synthesized by the in situ reactions of Schiff bases derived from 3-(phenyl/substituted phenyl)-4-amino-5-hydrazino-1,2,4-triazoles, salicyldehyde/ 2-hydroxy-1-naphthaldehyde and 1,4-dibromobutane/1,5-dibromopentane in presence of zinc(II) acetate dihydrate in absolute ethanol. The structures of all these zinc(II) complexes were established on the basis of elemental analyses and spectral data (IR, 1H NMR and 13C NMR). Scanning electron microscopy studies have been carried out to investigate the particle size and surface morphology of a particular complex while thermal studies confirm the presence of coordinated water molecules in all the zinc(II) complexes. The antimicrobial effects of all the synthesized complexes were studied against different species of pathogenic fungi and bacteria.
Synthesis and spectral characterization of Zn(II) microsphere series for antimicrobial application
Singh, Ajay K.,Pandey, Sarvesh K.,Pandey,Sengupta
, p. 376 - 383 (2014/07/21)
Microsphere series have been synthesized by reacting zinc(II) acetate dihydrate with Schiff bases derived from 2-hydrazino-5-[substituted phenyl]-1,3,4-thiadiazole/oxadiazole/triazole with salicylaldehyde. Elemental analysis suggests that the complexes have 1:2 and 1:1 stoichiometry of the type [Zn(L)2(H2O)2] and [Zn(L′)(H 2O)2]; LH = Schiff bases derived from 2-hydrazino-5- [substituted phenyl]-1,3,4-thia/oxadiazole with salicylaldehyde; L′H 2 = Schiff bases derived from 3-(substituted phenyl)-4-amino-5- hydrazino-1,2,4-triazole and salicylaldehyde and were characterized by elemental analyses, IR, 1H NMR and 13C NMR spectral data. Scanning electron microscopy (SEM) showed that synthesized materials have microsphere like structure and there EDX analysis comparably matches with elemental analysis. For the antimicrobial application Schiff bases and their zinc(II) complexes were screened for four bacteria e.g. Bacillus subtilis, Pseudomonas aeruginosa, Salmonella typhi, Streptococcus pyogenes and four fungi e.g. Cyrtomium falcatum, Aspergillus niger, Fusarium oxysporium and Curvularia pallescence by the reported method. Schiff base and Zn(II) compounds showed significant antimicrobial activities. However, activities increase upon chelation. Thermal analysis (TGA) data of compound (10) showed its stability up to 300 °C.
