118577-14-3Relevant academic research and scientific papers
A One-Pot Process for the Enantioselective Synthesis of Amines via Reductive Amination under Transfer Hydrogenation Conditions
Williams, Glynn D.,Pike, Richard A.,Wade, Charles E.,Wills, Martin
, p. 4227 - 4230 (2007/10/03)
(Equation presented) Cyclic amines may be prepared via a sequence of deprotection followed by intramolecular reductive amination of t-Boc-protected amino ketones under asymmetric transfer hydrogenation conditions. In cases where the corresponding imine reaction proceeds with high enantioselectivity, this is reflected in the one-step process.
