118584-90-0

Basic information

• Product Name: FMOC-L-LYS(DANSYL)-OH
• Synonyms: FMOC-L-LYS(DANSYL)-OH;N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N-EPSILON-DANSYL-L-LYSINE;N-(9-Fluorenylmethyloxycarbonyl)-N'-dansyl-L-lysine;N-Fmoc-N'-dansyl-L-lysine;Fmoc-Lys(dansyl)-OH;Nα-Fmoc-Nε-dansyl-L-lysine≥ 97% (HPLC);(9H-Fluoren-9-yl)MethOxy]Carbonyl Lys(Dansyl)-OH;(2S)-6-[[5-(dimethylamino)naphthalen-1-yl]sulfonylamino]-2-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoic acid
• CAS NO: 118584-90-0
• Molecular Formula: C33H35N3O6S
• Molecular Weight: 601.71
• Mol File: 118584-90-0.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: FMOC-L-LYS(DANSYL)-OH(CAS DataBase Reference)
• NIST Chemistry Reference: FMOC-L-LYS(DANSYL)-OH(118584-90-0)
• EPA Substance Registry System: FMOC-L-LYS(DANSYL)-OH(118584-90-0)

Safety Data

• Hazardous Substances Data: 118584-90-0(Hazardous Substances Data)

Usage

Chemical Properties

White powder

Uses

Fmoc-Lys(dansyl)-OH is a dansylated peptides as a substrate for fluorometric proteolytic enzyme assays.

Upstream product

• 605-65-2 5-(dimethylamino)naphth-1-ylsulfonyl chloride 
• 105047-45-8 Fmoc-Lys-OH 

Downstream Products

• 1435485-71-4 C₆₇H₈₅N₁₅O₉S 

Relevant articles and documents

Efficient N-terminal labeling of proteins by use of sortase

"Sorting out" N-terminal labeling: The reversibility of transpeptidase reactions makes protein N-terminal labeling challenging. Depsipeptide substrates for sortase A release alcohol by-products, which are poor nucleophiles for the reverse reaction, during ligation. Proteins with an unhindered N-terminal glycine residue can be labeled efficiently with only a minimal excess of the labeling reagent (see scheme).

Synthese Bor-reicher Lysindendrimere zur Proteinmarkierung in der Elektronenmikroskopie

Keywords: Borverbindungen; Dendrimere; Elektronenmikroskopie; Festphasensynthese; Peptide