1185915-33-6Relevant articles and documents
Synthesis, cannabinoid receptor affinity, molecular modeling studies and in vivo pharmacological evaluation of new substituted 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides. 2. Effect of the 3-carboxamide substituent on the affinity and selectivity
Silvestri, Romano,Ligresti, Alessia,Regina, Giuseppe La,Piscitelli, Francesco,Gatti, Valerio,Brizzi, Antonella,Pasquini, Serena,Lavecchia, Antonio,Allara, Marco,Fantini, Noemi,Carai, Mauro Antonio Maria,Novellino, Ettore,Colombo, Giancarlo,Marzo, Vincenzo Di,Corelli, Federico
experimental part, p. 5549 - 5564 (2009/12/05)
New substituted 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides were synthesized by replacing the 2,4-dichlorobenzyl and cyclohexyl moieties at the 3-carboxamide nitrogen of the previously reported CB1 receptor antagonists/inverse agonists