1185984-75-1

Basic information

• Product Name: ethyl (R)-4-(4-methoxyphenyl)-2-(nitromethyl)-4-oxobutanoate
• Synonyms: ethyl (R)-4-(4-methoxyphenyl)-2-(nitromethyl)-4-oxobutanoate
• CAS NO: 1185984-75-1
• Molecular Weight: 295.292
• Mol File: 1185984-75-1.mol

Chemical Properties

• CAS DataBase Reference: ethyl (R)-4-(4-methoxyphenyl)-2-(nitromethyl)-4-oxobutanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl (R)-4-(4-methoxyphenyl)-2-(nitromethyl)-4-oxobutanoate(1185984-75-1)
• EPA Substance Registry System: ethyl (R)-4-(4-methoxyphenyl)-2-(nitromethyl)-4-oxobutanoate(1185984-75-1)

Safety Data

• Hazardous Substances Data: 1185984-75-1(Hazardous Substances Data)

Upstream product

• 127427-28-5 trans-ethyl-4-(4-methoxyphenyl)-4-oxobut-2-enoate 
• 75-52-5 nitromethane 

Downstream Products

• 1185985-44-7 1-ethyl 4-(4-methoxyphenyl) (R)-2-(nitromethyl)succinate 
• 919513-66-9 ethyl (R)-5-oxopyrrolidine-3-carboxylate 

Relevant articles and documents

Highly enantioselective organocatalytic Michael addition of nitroalkanes to 4-oxo-enoates

A useful Michael addition reaction using nitroalkanes as the nucleophile and 4-oxo-enoates as the Michael acceptor has been disclosed, and the reaction allows expedient access to functionalized chiral γ-keto esters in high yields and excellent enantioselectivities (up to 98% ee), with a low catalyst loading.