1186004-10-3

Usage

Type of drug

Nonsteroidal anti-inflammatory drug (NSAID)

Main properties

Potent analgesic and anti-inflammatory properties

Mechanism of action

Inhibits the production of prostaglandins, which are chemicals in the body that cause pain and inflammation

Uses

Relief of moderate to severe pain, especially after surgery or in conditions such as arthritis

Side effects (potential)

Gastrointestinal and renal issues with long-term use

Treatment duration

Often used for short-term pain relief

Supervision

Should be used judiciously under medical supervision

Effectiveness

Effective option for managing acute pain and inflammation when used properly.

Upstream product

• 101829-74-7 diethyl 4-picolylmalonate 
• 73870-24-3 4-bromomethyl pyridine hydrobromide 
• 100-43-6 4-vinylpyridine 

Relevant academic research and scientific papers

Vinylpyridines as Building Blocks for the Photocatalyzed Synthesis of Alkylpyridines

The photocatalyzed addition of several hydrogen donors (ethers, aldehydes, alkanes, amides) onto vinylpyridines was achieved. This approach provided access to alkylpyridines, which are important building blocks for the preparation of compounds with biological activity. The strategy was very simple and straightforward because it required only a small amount of a cheap decatungstate salt as photocatalyst. As an added advantage, the reaction could be performed under sunlight irradiation as well as under flow conditions.

Short & expedient synthesis of pyridine containing dihydrochalcone 1-(2-hydroxyphenyl)-3-(pyridin-4-yl)propan-1-one: A non-nutritive artificial sweetener

An efficient synthesis of the artificial sweetener 1-(2-hydroxyphenyl)-3-(pyridin-4- yl)propan-1-one employing Fries Rearrangement as a key step in the construction of pyridine containing dihydrochalcone is reported. A novel approach for the synthesis of

Flavor Molecules

A method of providing a range of flavors to an orally-receivable or ingestible product, the method including adding at least one compound, including salts thereof, of the formula: wherein R1 may be H, OH, O(CH2)2OH, OCH2OCH3 or R2 may be selected from a range of 5- and 6-membered heterocyclic rings, and wherein R3 may be H or OH. The compounds give rise to a wide range of flavors, and some are useful as sweetness enhancers, this allowing sweetener content to be reduced while maintaining sweetness. Also disclosed are orally-receivable or ingestible products including the compounds.