1186012-01-0Relevant academic research and scientific papers
METHOD FOR DETECTION OF METHYLCYTOSINE USING PHOTORESPONSIVE PROBE
-
Page/Page column 14; 15, (2011/01/11)
The present invention provides a method for detecting methylcytosine in DNA rapidly, conveniently, and with high sensitivity. The present invention relates to a method for detecting methylcytosine by using a methylcytosine photocoupling agent (a photoresp
Detection of methylcytosine by DNA photoligation via hydrophobic interaction of the alkyl group
Ogino, Masayuki,Taya, Yuuta,Fujimoto, Kenzo
supporting information; experimental part, p. 3163 - 3167 (2011/02/25)
We report the nonenzymatic detection of 5-methylcytosine by using template-directed photoligation through 5-vinyl-2′-deoxyuridine derivatives with high selectivity. In this paper, we propose a new detection method by using hydrophobic interaction. The photoligation yield of the 5-methylcytosine case was approximately 5.6-fold higher than that in the case of cytosine.
