1186016-33-0

Upstream product

• 639090-55-4 N-[4-({4-chloro-6-[(3-methyl-1H-pyrazol-5-yl)amino]pyrimidin-2-yl}sulfanyl)phenyl]cyclopropane carboxamide 
• 112257-22-4 piperazine-1-acetic acid tert-butyl ester 

Downstream Products

• 1186016-45-4 C₂₄H₂₈N₈O₃S 

Relevant academic research and scientific papers

AURORA KINASE INHIBITORS FROM AN ENCODED SMALL MOLECULE LIBRARY

The present invention provides, at least in part, compounds of formula I: or a pharmaceutically acceptable salt thereof, wherein Z1, Z2, Z3, R1, x, y, R2, R3, R4a, R4b

P38 KINASE INHIBITORS

Compounds of formula (I) and (Il) are disclosed, as well as methods for their identification, their preparation, pharmaceutical compositions containing them, and their use in treating disease. The compounds inhibit the production of TNF-alpha and interleu