1186132-05-7Relevant articles and documents
Synthesis and biological activity of α-galactosyl ceramide KRN7000 and galactosyl (α1→2) galactosyl ceramide
Veerapen, Natacha,Brigl, Manfred,Garg, Salil,Cerundolo, Vincenzo,Cox, Liam R.,Brenner, Michael B.,Besra, Gurdyal S.
, p. 4288 - 4291 (2009)
We herein report a faster and less cumbersome synthesis of the biologically attractive, α-galactosyl ceramide (α-GalCer), known as KRN7000, and its analogues. More importantly, the use of a silicon tethered intramolecular glycosylation reaction gave easy