1186231-83-3 Usage
General Description
TAK-441 is a chemical compound developed by Takeda pharmaceuticals with potential antineoplastic activity—meaning it has the ability to inhibit the maturation and proliferation of malignant cells. Initially, TAK-441 was investigated for the treatment of different types of cancer, including pancreatic cancer, due to its activity as a Par-1 antagonist. Par-1 (Protease-activated receptor 1) is often over expressed in many types of cancer, and its suppression can inhibit cancer cell growth. Although it showed promise in early studies, there is currently no definitive clinical data confirming its efficacy as a cancer treatment.
Check Digit Verification of cas no
The CAS Registry Mumber 1186231-83-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,8,6,2,3 and 1 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1186231-83:
(9*1)+(8*1)+(7*8)+(6*6)+(5*2)+(4*3)+(3*1)+(2*8)+(1*3)=153
153 % 10 = 3
So 1186231-83-3 is a valid CAS Registry Number.
1186231-83-3Relevant articles and documents
FUSED HETEROCYCLIC RING DERIVATIVE AND USE THEREOF
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, (2012/07/14)
The present invention provides a fused heterocycle derivative having a strong Smo inhibitory activity, and use thereof. Specially, the present invention relates to a compound represented by the formula wherein each symbol is as defined in the specificatio
