1186236-75-8 Usage
Uses
Used in Pharmaceutical Industry:
1-[1,1'-Biphenyl]-4-ylethenyl Ester 1-Piperidinecarboxylic Acid is used as an inhibitor of fatty acid amide hydrolase (FAAH) for its analgesic effects. The inhibition of FAAH leads to an increase in the levels of endocannabinoids, which are known to play a role in pain relief and other physiological processes. This makes the compound a promising candidate for the development of new analgesic drugs.
Used in Pain Management:
As an FAAH inhibitor, 1-[1,1'-Biphenyl]-4-ylethenyl Ester 1-Piperidinecarboxylic Acid is used for its potential to provide pain relief in various conditions. The analgesic effects of this molecule can be beneficial in managing chronic pain, post-operative pain, and other pain-related disorders.
Used in Neurological Disorders:
Due to the involvement of the endocannabinoid system in various neurological processes, 1-[1,1'-Biphenyl]-4-ylethenyl Ester 1-Piperidinecarboxylic Acid may also have potential applications in the treatment of neurological disorders. The modulation of endocannabinoid levels through FAAH inhibition could help in managing symptoms associated with conditions such as multiple sclerosis, neuropathic pain, and anxiety disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 1186236-75-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,8,6,2,3 and 6 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1186236-75:
(9*1)+(8*1)+(7*8)+(6*6)+(5*2)+(4*3)+(3*6)+(2*7)+(1*5)=168
168 % 10 = 8
So 1186236-75-8 is a valid CAS Registry Number.
1186236-75-8Relevant academic research and scientific papers
Enol carbamates as inhibitors of fatty acid amide hydrolase (FAAH) endowed with high selectivity for FAAH over the other targets of the endocannabinoid system
Gattinoni, Sonia,De Simone, Chiara,Dallavalle, Sabrina,Fezza, Filomena,Nannei, Raffaella,Amadio, Daniele,Minetti, Patrizia,Quattrociocchi, Gianandrea,Caprioli, Antonio,Borsini, Franco,Cabri, Walter,Penco, Sergio,Merlini, Lucio,Maccarrone, Mauro
scheme or table, p. 357 - 360 (2010/11/18)
FAAH inhibitors: This study identifies a new class of enol carbamates as potent reversibleinhibitors of fatty acid amide hydrolase (FAAH), endowed with high selectivity towards this target over other components of endocannabinoid system.
ENOL CARBAMATE DERIVATIVES AS MODULATORS OF FATTY ACID AMIDE HYDROLASE
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Page/Page column 23-24, (2009/10/22)
The invention provides novel enol carbamate derivatives of formula (I) for inhibiting Fatty Acid Amide Hydrolase (FAAH), compositions that include such compounds as well as methods of treating diseases of energy metabolism, central nervous system disorder
