Cas 1186332-23-9,3-(4-chloro-3-methoxy-phenyl)-7-[4-(8-methyl-3,8-diaza-bicyclo[3.2.1]oct-3-yl)-phenyl]-2-pyridin-4-yl-pyrazolo[1,5-a]pyrimidine

1186332-23-9

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Basic information

Product Name: 3-(4-chloro-3-methoxy-phenyl)-7-[4-(8-methyl-3,8-diaza-bicyclo[3.2.1]oct-3-yl)-phenyl]-2-pyridin-4-yl-pyrazolo[1,5-a]pyrimidine
Synonyms:
CAS NO:1186332-23-9
Molecular Formula:
Molecular Weight: 537.064
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 3-(4-chloro-3-methoxy-phenyl)-7-[4-(8-methyl-3,8-diaza-bicyclo[3.2.1]oct-3-yl)-phenyl]-2-pyridin-4-yl-pyrazolo[1,5-a]pyrimidine(CAS DataBase Reference)
NIST Chemistry Reference: 3-(4-chloro-3-methoxy-phenyl)-7-[4-(8-methyl-3,8-diaza-bicyclo[3.2.1]oct-3-yl)-phenyl]-2-pyridin-4-yl-pyrazolo[1,5-a]pyrimidine(1186332-23-9)
EPA Substance Registry System: 3-(4-chloro-3-methoxy-phenyl)-7-[4-(8-methyl-3,8-diaza-bicyclo[3.2.1]oct-3-yl)-phenyl]-2-pyridin-4-yl-pyrazolo[1,5-a]pyrimidine(1186332-23-9)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 1186332-23-9(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 1186332-23-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,8,6,3,3 and 2 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1186332-23:
(9*1)+(8*1)+(7*8)+(6*6)+(5*3)+(4*3)+(3*2)+(2*2)+(1*3)=149
149 % 10 = 9
So 1186332-23-9 is a valid CAS Registry Number.

1186332-23-9Upstream product

51102-42-2 8-methyl-3,8-diazabicyclo[3,2,1]octane

1186332-23-9Downstream Products

1186332-25-1 2-chloro-5-{7-[4-(8-methyl-3,8-diaza-bicyclo[3.2.1]oct-3-yl)-phenyl]-2-pyridin-4-yl-pyrazolo[1,5-a]pyrimidin-3-yl}-phenol

1186332-23-9Relevant academic research and scientific papers

Discovery of highly potent and selective type I B-Raf kinase inhibitors

Wang, Xiaolun,Berger, Dan M.,Salaski, Edward J.,Torres, Nancy,Hu, Yongbo,Levin, Jeremy I.,Powell, Dennis,Wojciechowicz, Donald,Collins, Karen,Frommer, Eileen

scheme or table, p. 6571 - 6574 (2010/06/12)

A series of pyrazolo[1,5-α]pyrimidine analogs has been prepared and found to be potent and selective B-Raf inhibitors. Molecular modeling suggests they bind to the active conformation of the enzyme.

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