1186391-39-8Relevant articles and documents
Ming-Phos/Gold(I)-Catalyzed Stereodivergent Synthesis of Highly Substituted Furo[3,4-d][1,2]oxazines?
Ji, Danting,Xu, Bing,Zhang, Junliang,Zhang, Zhan-Ming,Zhou, Lujia
, p. 577 - 582 (2020)
A gold(I)-catalyzed asymmetric intermolecular tandem [3+3]-cyclization reaction of 2-(1-alkynyl)-2- alken-1-ones with nitrones has been developed by using Ming-Phos as a chiral ligand. This method enables access to the stereodivergent synthesis of highly substituted furo[3,4-d][1,2]oxazines in excellent efficiency and stereoselectivity (up to 99% yield, 99% ee, >20 : 1 dr).