1186410-75-2Relevant academic research and scientific papers
Potent and selective adenosine A2A receptor antagonists: [1,2,4]-triazolo[4,3-c]pyrimidin-3-ones
Harris, Joel M.,Neustadt, Bernard R.,Zhang, Hongtao,Lachowicz, Jean,Cohen-Williams, Mary,Varty, Geoff,Hao, Jinsong,Stamford, Andrew W.
, p. 2497 - 2501 (2011/05/15)
Antagonism of the adenosine A2A receptor affords a possible treatment of Parkinson's disease. In the course of investigating pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine A2A antagonists, we prepared [1,2,4]-triazolo[4,3-c]pyrimidi
1,2,4-TRIAZOLO[4,3-C]PYRIMIDIN-3-ONE AND PYRAZOLO [4,3-E] -1,2,4-TRIAZOLO [4,3-C] PYRIMIDIN-3-ONE COMPOUNDS FOR USE AS ADENOSINE A2A RECEPTOR ANTAGONISTS
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Page/Page column 38-39, (2009/10/22)
Compounds of the Formula I wherein R1 and R2 together with the carbon atoms to which they are bonded optionally form a further heteroaromatic ring of the formula (II) as well as pharmaceutically acceptable salts, solvates, esters and
