118656-50-1

Upstream product

• 118656-42-1 ((1S,2S)-2-Methyl-1-phenylsulfanylmethyl-butyl)-carbamic acid tert-butyl ester 
• 132149-84-9 ((1R,2S)-2-Methyl-1-phenylsulfanylmethyl-butyl)-carbamic acid tert-butyl ester 
• 882-33-7 diphenyldisulfane 
• 132149-83-8 ((1R,2S)-1-Benzyloxymethyl-2-methyl-butyl)-carbamic acid tert-butyl ester 
• 132149-82-7 ((2S,3S)-2-Methoxymethoxy-3-methyl-pentyloxymethyl)-benzene 
• 106946-74-1 Boc-D-allo-isoleucinol 
• 56577-28-7 methyl (2S,3S)-2-hydroxy-3-methylpentanoate 

Downstream Products

• 118656-57-8 (4S,5R)-3-Acetyl-4-((R)-sec-butyl)-5-phenylsulfanyl-oxazolidin-2-one 
• 118656-57-8 (4S,5S)-3-Acetyl-4-((R)-sec-butyl)-5-phenylsulfanyl-oxazolidin-2-one 
• 118656-75-0 (4S,5S)-3-Acetyl-5-allyl-4-sec-butyl-oxazolidin-2-one 

Relevant academic research and scientific papers

THE KINETIC STUDY ON THE DESULFURIZATION OF 4,5-TRANS- AND 4,5-CIS-5-PHENYLTHIOOXAZOLIDIN-2-ONES VIA CYCLIC CARBAMOYLOXYRADICAL SPECIES

The relative rate for generation of cyclic carbamoyloxy radicals from 4,5-trans-5-phenylthiooxazolidin-2-ones (6a-c) and cis-isomers (7a-c) was determined and trans-isomers were found to be about six times as reactive as cis-isomers by comparison with their half life.

HIGHLY DIASTEREOSELECTIVE SYNTHESIS OF N-BOC DOLAISOLEUINE, UNUSUAL AMINO ACID IN DOLASTATIN 10

Photolysis of 5-phenylthiooxazolidin-2-one (4) in the presence of (n-Bu3Sn)2 and n-Bu3SnCH2CH=CH2 afforded 5-allyl derivative (5) which was led to N-Boc dolaisoleuine (11), one component of dolastatine 10 (2), via 6-10.