1186586-33-3Relevant academic research and scientific papers
Development of N-[11C]methylamino 4-hydroxy-2(1H)-quinolone derivatives as PET radioligands for the glycine-binding site of NMDA receptors
Fuchigami, Takeshi,Haradahira, Terushi,Fujimoto, Noriko,Nojiri, Yumiko,Mukai, Takahiro,Yamamoto, Fumihiko,Okauchi, Takashi,Maeda, Jun,Suzuki, Kazutoshi,Suhara, Tetsuya,Yamaguchi, Hiroshi,Ogawa, Mikako,Magata, Yasuhiro,Maeda, Minoru
experimental part, p. 5665 - 5675 (2009/12/09)
In this study, we synthesized and evaluated several amino 4-hydroxy-2(1H)-quinolone (4HQ) derivatives as new PET radioligand candidates for the glycine site of the NMDA receptors. Among these ligands, we discovered that 7-chloro-4-hydroxy-3-{3-(4-methylam
