118664-22-5

Upstream product

• 118664-21-4 (3S,4aS)-4a-Methyl-3-phenylsulfanyl-3,4,4a,5,6,7-hexahydro-1H-quinolin-2-one 
• 73739-21-6 (R,Z)-N-(2-methylcyclohexylidene)-1-phenylethaneamine 
• 118664-20-3 (S)-3-((S)-1-Methyl-2-oxo-cyclohexyl)-2-phenylsulfanyl-propionic acid methyl ester 

Relevant academic research and scientific papers

THE ASYMMETRIC MICHAEL ADDITION PROCESS INVOLVING CHIRAL IMINES : STEREOCHEMICAL DATA IN SUPPORT OF A CYCLIC-LIKE TRANSITION STATE

Addition of imine 4 to Michael acceptors 5 and 8 are both highly selective processes.The observed stereocontrol of the newly created asymmetric centers in the resulting adducts strongly supports cyclic-like transition states.