1186648-12-3

Basic information

• Product Name: 2-amino-5-benzoyl-4-(5-bromo-3-pyridinyl)-1-[(4-methoxyphenyl)sulfonyl]-1H-pyrrole-3-carbonitrile
• Synonyms: 2-amino-5-benzoyl-4-(5-bromo-3-pyridinyl)-1-[(4-methoxyphenyl)sulfonyl]-1H-pyrrole-3-carbonitrile
• CAS NO: 1186648-12-3
• Molecular Weight: 537.393
• Mol File: 1186648-12-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-amino-5-benzoyl-4-(5-bromo-3-pyridinyl)-1-[(4-methoxyphenyl)sulfonyl]-1H-pyrrole-3-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-5-benzoyl-4-(5-bromo-3-pyridinyl)-1-[(4-methoxyphenyl)sulfonyl]-1H-pyrrole-3-carbonitrile(1186648-12-3)
• EPA Substance Registry System: 2-amino-5-benzoyl-4-(5-bromo-3-pyridinyl)-1-[(4-methoxyphenyl)sulfonyl]-1H-pyrrole-3-carbonitrile(1186648-12-3)

Safety Data

• Hazardous Substances Data: 1186648-12-3(Hazardous Substances Data)

Upstream product

• 113118-81-3 5-bromopyridine-3-carbaldehyde 
• 933025-26-4 4-methoxy-N-(2-oxo-2-phenylethyl)benzenesulfonamide 

Relevant articles and documents

One-pot multicomponent synthesis of diversely substituted 2-aminopyrroles. A short general synthesis of rigidins A, B, C, and D

Privileged medicinal scaffolds based on the structures of tetra-and pentasubstituted 2-aminopyrroles were prepared via one-pot multicomponent reactions of structurally diverse aldehydes and N-(aryl-, hetaryl-, alkylsulfonamido)acetophenones with activated methylene compounds. This methodology was used in a four-step synthesis of alkaloids rigidins A, B, C, and D in overall yields of 61%, 58%, 60%, and 53%, respectively. Of these, rigidins B, C, and D were synthesized for the first time.(Figure Presented)